Ammadelle was designed in 1857 by Calvert Vaux, co-designer of Central Park in New York City. Vaux was more widely known for his landscape architecture, and he also designed the 7-acre site on which Ammadelle sits. The style is Italianate and was built between 1859-1861.
According to the nomination form for the National Register of Historic Places, 1974, three first-floor mantels were replaced in the 19th century and the kitchen was “modernized” but otherwise, the building retains original features that were in place at the time of the nomination. The antebellum structure had been completed prior to the beginning of the Civil War, with the exception of the rear balconies and a wine cellar. The outbreak of war disrupted the completion of those features, and they were never added.